Nanodisc-based approach to enhance DEER measurements
We use spin-nanodisc to improve SNR of DEER signals for conventional membrane protein study. The new approach enables a significant improvement in the distance resolution obtainable from the DEER result by Tikhonov method.
ESR reveals lipid-dependent conformational changes of membrane proteins
Membrane proteins are incorporated in various environments, including detergent, membrane vesicles, and nanodisc. ESR distance measurements show that the protein behave differently with environments.