The CHIANG LAB
- Publications
- …
- Publications
The CHIANG LAB
- Publications
- …
- Publications
Selected Publications
We invite you to explore our publications.
Biophysical/Bioinorganic Chemistry
- H.Y. Chen, R.F. Tsai, Y.S. Lu, Y.C. Cheng, H.Y. Fan-Chiang, C.Y. Wu, F.C. Lo, H.W. Kuo, W.K. Yang, W.Y. Liao, N.J. Hu*, S.C. Sue*, Y.W. Chiang*, Structure and Nitrite Reductase Activity of the Di-iron Protein ScdA in Staphylococcus aureus, Journal of the American Chemical Society, 147 (2025) 31558-31569.
- C.L. Hung, W.H. Wang, Y.C. Chang, Y.C. Lai*, Y.W. Chiang*, Electrostatic Clamp and Loop Dynamics Dictate Caspase‑8 Cleavage of the Apoptotic Protein Bid, The Journal of Physical Chemistry Letters, 16 (2025) 7522-7529.
- R.F. Tsai, H.Y. Chen, Y.C. Cheng, F.C. Lo, T.T. Lu, W.F. Liaw, Y.W. Chiang*, Regulatory Mechanisms and Synergistic Enhancement of the Diiron YtfE Protein in Nitric Oxide Reduction, Chemistry − A European Journal, (2025) e202403680.
- C.C. Cheng, R.F. Tsai, C.K. Lin, K.T. Tan, V. Kalendra, M. Simenas, C.W. Lin*, and Y.W. Chiang*, In-Cell DEER Spectroscopy of Nanodisc-Delivered Membrane Proteins in Living Cell Membranes, JACS Au, 4 (2024) 3766-3770.
- P.S. Yeh, C.C. Li, Y.S. Lu, and Y.W. Chiang*, Structural Insights into the Binding and Degradation Mechanisms of Protoporphyrin IX by the Translocator Protein TSPO, JACS Au, 3 (2023) 2918-2929.
- C.L. Hung, H.H. Chang, S.W. Lee, Y.W. Chiang*, Stepwise activation of the pro-apoptotic protein Bid at mitochondrial membranes, Cell Death & Differentiation, 28 (2021) 1910-1925).
- C.C. Li, T.Y. Kao, C.C. Cheng, Y.W. Chiang*, Structure and regulation of the BsYetJ calcium channel in lipid nanodiscs, Proceedings of the National Academy of Sciences (PNAS), 117 (2020) 30126-30134.
- Y.J. Lan, P.S. Yeh, T.Y. Kao, Y.C. Lo, S.C. Sue, Y.W. Chen, D.W. Hwang*, Y.W. Chiang*, Anti-apoptotic BCL-2 regulation by changes in dynamics of its long unstructured loop, Communications Biology, 3 (2020) 668.
- R.F. Tsai, N.C. Lin, T.Y. Kao, Y.H. Kuo, F.C. Lo, W.F. Liaw, Y.W. Chiang*, Nitrosylation of the Diiron Core Mediated by the N Domain of YtfE, The Journal of Physical Chemistry Letters, 11 (2020) 8538-8542.
- Y.C. Lai, C.C. Li, T.C. Sung, C.W. Chang, Y.J. Lan, and Y.W. Chiang*, The Role of Cardiolipin in Promoting the Membrane Pore-forming Activity of BAX Oligomers, BBA Biomembranes, 1861 (2019) 268-280.
- C.L. Hung, Y.Y. Lin, H.H. Chang, and Y.W. Chiang*, Accessing local structural disruption of Bid protein during thermal denaturation by absorption-mode ESR spectroscopy, RSC Advances, 8 (2018) 34656-34669.
- F.C. Lo, C.C. Hsieh, M. Maestre-Reyna*, C.Y. Chen*, T.P. Ko, Y.C. Horng, Y.C. Lai, YW Chiang*, C.M. Chou, C.H. Chiang, W.N. Huang, Y.H. Lin, D.S. Bohle*, W.F. Liaw*, Crystal Structure Analysis of the Repair of Iron Centers Protein YtfE and its Interaction with NO, Chemistry − A European Journal, 22 (2016) 9768-9776.
- T.C. Sung, C.Y. Li, Y.C. Lai, C.L. Hung, O. Shih, Y.Q. Yeh, U.S. Jeng, and Y.W. Chiang*, Solution Structure of Apoptotic BAX Oligomer: Oligomerization Likely Precedes Membrane Insertion, Structure, 23 (2015) 1878-1888.
- C.J. Tsai, S. Liu, C.L. Hung, S.R. Jhong, T.C. Sung, and Y.W. Chiang*, BAX-induced Apoptosis Can Be Initiated Through A Conformational Selection Mechanism, Structure, 23 (2015) 139-148. (selected as featured article: Conformational Selection in the Heart of Apoptosis)
- Y.W. Chiang, Y. Shimoyama, G.W. Feigenson, J.H. Freed*, Dynamic Molecular Structure of DPPC-DLPC-Cholesterol Ternary Lipid System by Spin-Label Electron Spin Resonance, Biophysical Journal, 87 (2004) 2483-2496.
Physical Chemistry
- T.Y. Kao and Y.W. Chiang*, DEERefiner-assisted Structural Refinement Using Pulsed Dipolar Spectroscopy: A Study on Multidrug Transporter LmrP, Physical Chemistry Chemical Physics, 25 (2023) 24508-24517.
- P.S. Ho, T.Y. Kao, C.C. Li, Y.J. Lan, Y.C. Lai, and Y.W. Chiang*, Nanodisc Lipids Exhibit Singular Behaviors Implying Critical Phenomena, Langmuir, 38 (2022) 15372-15383.
- T.Y. Kao, C.L. Hung, Y.J. Lan, S.W. Lee, and Y.W. Chiang*, Simple Cryoprotectant-Free Method to Advance Pulsed Dipolar ESR Spectroscopy for Capturing Protein Conformational Ensembles, The Journal of Physical Chemistry B, 126 (2022) 423-429.
- C.L. Hung, Y.H. Kuo, S.W. Lee, and Y.W. Chiang*, Protein stability depends critically on the surface hydration bonding network: A Case of Bid Protein, The Journal of Physical Chemistry B, 125 (2021) 8373–8382.
- Y.H. Kuo and Y.W. Chiang*, Slow Dynamics around a Protein and Its Coupling to Solvent, ACS Central Science, 4 (2018) 645-655.
- K.J. Chang†, Y.H. Kuo†, and Y.W. Chiang*, Study of Protein Dynamics under Nanoconfinement by Spin-Label ESR: A Case of T4 Lysozyme Protein, The Journal of Physical Chemistry B, 121 (2017) 4355-4363.
- T.Y. Kao, C.J. Tsai, Y.J. Lan, and Y.W. Chiang*, Role of Conformational Heterogeneity in Regulating the Apoptotic Activity of BAX Protein, Physical Chemistry Chemical Physics, 19 (2017) 9584-9591.
- C.H. Chan, C.J. Tsai, and Y.W. Chiang*, Side-chain Packing Interactions Stabilize an Intermediate of BAX Protein Against Chemical and Thermal Denaturation, Journal of Physical Chemistry B, 119 (2015) 54-64.
- Y.C. Lai, Y.F. Chen, and Y.W. Chiang*, ESR Study of Interfacial Hydration Layers of Polypeptides in Water-Filled Nanochannels and in Vitrified Bulk Solvents, PLOS one, 8 (2013) e68264-13.
- C.J. Tsai, and Y.W. Chiang*, Effects of Anisotropic Nanoconfinement on Rotational Dynamics of Biomolecules: An Electron Spin Resonance Study, Journal of Physical Chemistry C, 116 (2012) 19798-19806.
- Y.W. Huang, Y.C. Lai, C.J. Tsai, and Y.W. Chiang*, Mesopores Provide an Amorphous State Suitable for Studying Biomolecular Structure at Cryogenic Temperatures, Proceedings of the National Academy of Sciences (PNAS), 108 (2011) 14145-14150.
- Y.W. Chiang, A.J. Costa-Filho, and J.H. Freed*, Dynamic Molecular Structure and Phase Diagram of DPPC-Cholesterol Binary Mixtures: A 2D-ELDOR Study, Journal of Physical Chemistry B, 111 (2007) 11260-11270.
- Y.W. Chiang, P.P. Borbat, and J.H. Freed*, Maximum Entropy: A Complement to Tikhonov Regularization for the Determination of Pair Distributions by Pulsed ESR, Journal of Magnetic Resonance, 177 (2005) 184-196.
- Y.W. Chiang, P.P. Borbat, J.H. Freed*, The Determination of Pair Distance Distributions by Pulsed ESR Using Tikhonov Regularization, Journal of Magnetic Resonance, 172 (2005) 279-295.
Inorganic/Organic Chemistry
- Y.C. Chan, H.X. Xiao, L. Qin, J.S. Shen, C.R. Yang, G.P.A. Yap, W.M. Ching, W.C. Chen,* Y.W. Chiang,* G. Frenking,* L. Zhao,* and T.G. Ong*, Isolated Carbon(I) Species Featuring a Carbone Cation Radical, Nature Synthesis, 4 (2025) 1278-1287 .
- A. Beniwal, D. Bhalothia, Y.R. Cheng, J.C. Kao, C. Yan, N. Hiraoka, H. Ishii, M. Cheng, Y.C. Lo, X. Tu, Y.W. Chiang, C.H. Wang, and T.Y. Chen*, Incorporation of Atomic Fe-Oxide Triggers a Quantum Leap in the CO2 Methanation Performance of Ni-Hydroxide, Chemical Engineering Journal, 493 (2024) 152834.
- S.Y. Fu, C.H. Chang, A.S. Ivanov, I. Popovs, J.L. Chen, Y.F. Liao, H.K. Liu, S. Chirra, Y.W. Chiang, J.C. Lee, W.L. Liu, W. Kaveevivitchai*, T.H. Chen*, Mixed-Valence CuI/CuIII Metal−Organic Frameworks with Non-innocent Ligand for Multielectron Transfer, Angew Chem Int Ed, (2023) e202312494.
- P. Dai*, Q. Wang, M. Xiang, T.M. Chen, X. Zhang, Y.W. Chiang, T.S. Chan, X. Wang*, Composition-Driven Anionic Disorder-Order Transformations Triggered Single-Eu2+-Converted High-Color-Rendering White-Light Phosphors, Chemical Engineering Journal, 380 (2020) 122508.
- J. Liu, M. Skaria, P. Sharma, Y.W. Chiang, and R.S. Liu*, Ground-State Dioxygen Undergoes Metal-Free [3+2]-Annulations with Allenes and Nitrosoarenes Under Ambient Conditions, Chemical Science, 8 (2017) 5482-5487.
- C.H. Ke, C.H. Chen, M.L. Tsai, H.C. Wang, F.T. Tsai, Y.W. Chiang, W.C. Shih, D.S. Bohle, and W.F. Liaw*, {Fe(NO)2}9 Dinitrosyl Iron Complex Acting as a Vehicle for the NO Radical, Journal of the American Chemical Society, 139 (2017) 67-70.
- C.C. Wang, H.C. Chang, Y.C. Lai, H. Fang, C.C. Li, H.K. Hsu, Z.Y. Li, T.S. Lin, T.S. Kuo, F. Neese, S. Ye*, Y.W. Chiang*, M.L. Tsai*, W.F. Liaw*, and W.Z. Lee*, A Structurally Characterized Nonheme Cobalt-Hydroperoxo Complex Derived from its Superoxo Intermediate via Hydrogen Atom Abstraction, Journal of the American Chemical Society, 138 (2016) 14186-14189.
- P. Dai, S.P. Lee, T.S. Chan, C.H. Huang, Y.W. Chiang, and T.M. Chen*, Sr3Ce(PO4)3:Eu2+: a broadband yellow-emitting phosphor for near ultraviolet-pumped white light-emitting devices, Journal of Materials Chemistry C, 4 (2016) 1170-1177.
- Q.B. Nguyen, C.L. Chen, Y.W. Chiang, and K.H. Lii* Cs3UGe7O18: A Pentavalent Uranium Germanate Containing Four- and Six-Coordinate Germanium, Inorganic Chemistry, 51 (2012) 3879-3882.
- H.L. Huang, Y.C. Lai, Y.W. Chiang, and S.L. Wang* Intrinsic Optical Properties and Divergent Doping Effects of Manganese(II) on Luminescence for Tin(II) Phosphite Grown from a Deep-Eutectic Solvent, Inorganic Chemistry, 51 (2012) 1986-1988.
Chiang Lab@NTHU